Drug interactions
Ergocalciferol + Mineral oil
Severity: Minor
Ergocalciferol and Mineral oil: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Oral mineral oil dissolves fat-soluble vitamins in the gut and carries them out in the stool, reducing vitamin D absorption. Chronic use may contribute to vitamin D deficiency.
What this interaction means in plain words
Ergocalciferol and Mineral oil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ergocalciferol belongs to Musculoskeletal; Mineral oil belongs to Gastrointestinal Tract.
Why it happens
Mineral oil acts as a lipophilic solvent that decreases intestinal absorption of fat-soluble vitamins.
What to do
Avoid regular use of mineral oil with vitamin D. If unavoidable, separate dosing by several hours and take vitamin D at a different time of day.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ergocalciferol
- Aluminum hydroxide + Ergocalciferol Moderate
- Calcium acetate + Ergocalciferol Moderate
- Calcium carbonate + Ergocalciferol Moderate
- Calcium chloride + Ergocalciferol Moderate
- Calcium citrate + Ergocalciferol Moderate
- Calcium gluconate + Ergocalciferol Moderate
Other interactions of Mineral oil
Frequently asked questions
Can I take Ergocalciferol with Mineral oil?
MediHelp rates the interaction as minor. Ergocalciferol and Mineral oil have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oral mineral oil dissolves fat-soluble vitamins in the gut and carries them out in the stool, reducing vitamin D absorption. Chronic use may contribute to vitamin D deficiency.
How serious is the interaction between Ergocalciferol and Mineral oil?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid regular use of mineral oil with vitamin D. If unavoidable, separate dosing by several hours and take vitamin D at a different time of day.
What other medicines interact with Ergocalciferol?
MediHelp also lists interactions of Ergocalciferol with, for example, Aluminum hydroxide, Calcium acetate, Calcium carbonate. The full list is on the Ergocalciferol page.
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