Drug interactions
Ertugliflozin-sitagliptin + Moxifloxacin
Severity: Moderate
Ertugliflozin-sitagliptin and Moxifloxacin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Moxifloxacin can disturb glucose control in diabetic patients, causing either hypoglycemia or hyperglycemia. The risk is lower than with some other quinolones but still relevant for patients on antidiabetic drugs.
What this interaction means in plain words
Ertugliflozin-sitagliptin and Moxifloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ertugliflozin-sitagliptin belongs to Endocrine; Moxifloxacin belongs to Anti Bacterial.
Why it happens
Fluoroquinolones alter pancreatic beta-cell insulin release, producing dysglycemia that adds to antidiabetic drug effects.
What to do
Monitor blood glucose during moxifloxacin therapy and educate the patient on symptoms of dysglycemia. Switch antibiotic class if glucose becomes unstable.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ertugliflozin-sitagliptin
Other interactions of Moxifloxacin
- Amiodarone + Moxifloxacin Contraindicated
- Arsenic trioxide + Moxifloxacin Contraindicated
- Disopyramide + Moxifloxacin Contraindicated
- Dofetilide + Moxifloxacin Contraindicated
- Dronedarone + Moxifloxacin Contraindicated
- Droperidol + Moxifloxacin Contraindicated
Frequently asked questions
Can I take Ertugliflozin-sitagliptin with Moxifloxacin?
MediHelp rates the interaction as moderate. Ertugliflozin-sitagliptin and Moxifloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Moxifloxacin can disturb glucose control in diabetic patients, causing either hypoglycemia or hyperglycemia. The risk is lower than with some other quinolones but still relevant for patients on antidiabetic drugs.
How serious is the interaction between Ertugliflozin-sitagliptin and Moxifloxacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose during moxifloxacin therapy and educate the patient on symptoms of dysglycemia. Switch antibiotic class if glucose becomes unstable.
What other medicines interact with Ertugliflozin-sitagliptin?
MediHelp also lists interactions of Ertugliflozin-sitagliptin with, for example, Albiglutide, Aripiprazole, Asenapine. The full list is on the Ertugliflozin-sitagliptin page.
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