Drug interactions
Everolimus + Human papillomavirus vaccine
Severity: Minor
Everolimus and Human papillomavirus vaccine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Everolimus is an immunosuppressant that may reduce the immune response to HPV vaccine. The non-live vaccine is safe, so the issue is reduced protection.
What this interaction means in plain words
Everolimus and Human papillomavirus vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Everolimus belongs to Oncology; Human papillomavirus vaccine belongs to Miscellaneous.
Why it happens
mTOR inhibition suppresses T-cell proliferation and may reduce vaccine immunogenicity.
What to do
Vaccinate on schedule, ideally before starting everolimus, and complete the full series.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Human papillomavirus vaccine
- Antithymocyte globulin equine + Human papillomavirus vaccine Moderate
- Antithymocyte globulin rabbit + Human papillomavirus vaccine Moderate
- Atidarsagene autotemcel + Human papillomavirus vaccine Moderate
- Belimumab + Human papillomavirus vaccine Moderate
- Cortisone + Human papillomavirus vaccine Moderate
- Cyclosporine + Human papillomavirus vaccine Moderate
Other interactions of Everolimus
- Bcg vaccine live + Everolimus Contraindicated
- Everolimus + Influenza virus vaccine quadrivalent intranasal Contraindicated
- Everolimus + Levoketoconazole Contraindicated
- Everolimus + Measles mumps and rubella vaccine live Contraindicated
- Everolimus + Measles mumps rubella and varicella vaccine live Contraindicated
- Everolimus + Measles vaccine Contraindicated
Frequently asked questions
Can I take Everolimus with Human papillomavirus vaccine?
MediHelp rates the interaction as minor. Everolimus and Human papillomavirus vaccine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Everolimus is an immunosuppressant that may reduce the immune response to HPV vaccine. The non-live vaccine is safe, so the issue is reduced protection.
How serious is the interaction between Everolimus and Human papillomavirus vaccine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Vaccinate on schedule, ideally before starting everolimus, and complete the full series.
What other medicines interact with Human papillomavirus vaccine?
MediHelp also lists interactions of Human papillomavirus vaccine with, for example, Antithymocyte globulin equine, Antithymocyte globulin rabbit, Atidarsagene autotemcel. The full list is on the Human papillomavirus vaccine page.
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