Drug interactions
Fondaparinux + Porfimer
Severity: Moderate
Fondaparinux and Porfimer: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Porfimer photodynamic therapy relies on light-activated damage to tissue and vasculature. Anticoagulants are listed as drugs that could reduce photodynamic effect by inhibiting thrombus formation, though clinical evidence is limited.
What this interaction means in plain words
Fondaparinux and Porfimer can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Fondaparinux belongs to Cardiovascular; Porfimer belongs to Miscellaneous.
Why it happens
Anticoagulation may reduce thrombosis-mediated vascular occlusion contributing to photodynamic tumor effect.
What to do
Assess whether anticoagulation is needed around photodynamic therapy and monitor treatment response and bleeding at the treated site.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Fondaparinux
- Defibrotide + Fondaparinux Contraindicated
- Fondaparinux + Ketorolac Contraindicated
- Abciximab + Fondaparinux Major
- Aceclofenac + Fondaparinux Major
- Acetylsalicylic acid + Fondaparinux Major
- Alteplase + Fondaparinux Major
Other interactions of Porfimer
Frequently asked questions
Can I take Fondaparinux with Porfimer?
MediHelp rates the interaction as moderate. Fondaparinux and Porfimer can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Porfimer photodynamic therapy relies on light-activated damage to tissue and vasculature. Anticoagulants are listed as drugs that could reduce photodynamic effect by inhibiting thrombus formation, though clinical evidence is limited.
How serious is the interaction between Fondaparinux and Porfimer?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Assess whether anticoagulation is needed around photodynamic therapy and monitor treatment response and bleeding at the treated site.
What other medicines interact with Fondaparinux?
MediHelp also lists interactions of Fondaparinux with, for example, Defibrotide, Ketorolac, Abciximab. The full list is on the Fondaparinux page.
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