Drug interactions
Glucagon + Lanreotide
Severity: Moderate
Glucagon and Lanreotide: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lanreotide suppresses secretion of both insulin and glucagon, which may alter glucose control. Endogenous glucagon counter-regulation may be blunted, though exogenous glucagon is still expected to act on the liver.
What this interaction means in plain words
Glucagon and Lanreotide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Glucagon belongs to Endocrine; Lanreotide belongs to Endocrine.
Why it happens
Somatostatin analog inhibition of pancreatic insulin and glucagon release.
What to do
Monitor blood glucose closely when starting or changing lanreotide and adjust antidiabetic therapy as needed. Ensure hypoglycemia rescue measures are available.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Glucagon and Lanreotide, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Lanreotide
- Lanreotide + Quinidine Major
- Alogliptin-metformin + Lanreotide Moderate
- Canagliflozin-metformin + Lanreotide Moderate
- Cyclosporin + Lanreotide Moderate
- Dapagliflozin-metformin + Lanreotide Moderate
- Empagliflozin-metformin + Lanreotide Moderate
Other interactions of Glucagon
- Atropine + Glucagon Moderate
- Benztropine + Glucagon Moderate
- Dicyclomine + Glucagon Moderate
- Diphenoxylate-atropine + Glucagon Moderate
- Glucagon + Glycopyrrolate Moderate
- Glucagon + Glycopyrronium Moderate
Frequently asked questions
Can I take Glucagon with Lanreotide?
MediHelp rates the interaction as moderate. Glucagon and Lanreotide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Lanreotide suppresses secretion of both insulin and glucagon, which may alter glucose control. Endogenous glucagon counter-regulation may be blunted, though exogenous glucagon is still expected to act on the liver.
How serious is the interaction between Glucagon and Lanreotide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose closely when starting or changing lanreotide and adjust antidiabetic therapy as needed. Ensure hypoglycemia rescue measures are available.
What other medicines interact with Lanreotide?
MediHelp also lists interactions of Lanreotide with, for example, Quinidine, Alogliptin-metformin, Canagliflozin-metformin. The full list is on the Lanreotide page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
