Drug interactions
Hawthorn + Hydroxyzine
Severity: Minor
Hawthorn and Hydroxyzine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hawthorn is reported to have mild sedative and hypotensive effects, so it may add to the drowsiness caused by hydroxyzine. The evidence is limited and largely theoretical.
What this interaction means in plain words
Hawthorn and Hydroxyzine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Hawthorn belongs to Gastrointestinal Tract; Hydroxyzine belongs to Respiratory.
Why it happens
Possible additive sedative effects; mechanism not well established.
What to do
Ask about herbal use and counsel patients to watch for increased drowsiness or dizziness.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Hydroxyzine
- Droperidol + Hydroxyzine Contraindicated
- Hydroxyzine + Pimozide Contraindicated
- Hydroxyzine + Thioridazine Contraindicated
- Hydroxyzine + Vandetanib Contraindicated
- Alfentanil + Hydroxyzine Major
- Amiodarone + Hydroxyzine Major
Other interactions of Hawthorn
- Amiodarone + Hawthorn Moderate
- Digoxin + Hawthorn Moderate
- Disopyramide + Hawthorn Moderate
- Encainide + Hawthorn Moderate
- Hawthorn + Ibutilide Moderate
- Hawthorn + Procainamide Moderate
Frequently asked questions
Can I take Hawthorn with Hydroxyzine?
MediHelp rates the interaction as minor. Hawthorn and Hydroxyzine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Hawthorn is reported to have mild sedative and hypotensive effects, so it may add to the drowsiness caused by hydroxyzine. The evidence is limited and largely theoretical.
How serious is the interaction between Hawthorn and Hydroxyzine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Ask about herbal use and counsel patients to watch for increased drowsiness or dizziness.
What other medicines interact with Hydroxyzine?
MediHelp also lists interactions of Hydroxyzine with, for example, Droperidol, Pimozide, Thioridazine. The full list is on the Hydroxyzine page.
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