Drug interactions
Human papillomavirus vaccine + Hydroxychloroquine
Severity: Minor
Human papillomavirus vaccine and Hydroxychloroquine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Hydroxychloroquine is only a mild immunomodulator and has not been shown to meaningfully impair responses to non-live vaccines. The HPV vaccine can be given during therapy.
What this interaction means in plain words
Human papillomavirus vaccine and Hydroxychloroquine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Human papillomavirus vaccine belongs to Miscellaneous; Hydroxychloroquine belongs to Musculoskeletal.
Why it happens
Mild immunomodulation through effects on antigen processing and cytokine signaling, with little expected impact on vaccine response.
What to do
No change needed; vaccinate according to the usual schedule.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Human papillomavirus vaccine
- Antithymocyte globulin equine + Human papillomavirus vaccine Moderate
- Antithymocyte globulin rabbit + Human papillomavirus vaccine Moderate
- Atidarsagene autotemcel + Human papillomavirus vaccine Moderate
- Belimumab + Human papillomavirus vaccine Moderate
- Cortisone + Human papillomavirus vaccine Moderate
- Cyclosporine + Human papillomavirus vaccine Moderate
Other interactions of Hydroxychloroquine
- Arsenic trioxide + Hydroxychloroquine Contraindicated
- Cisapride + Hydroxychloroquine Contraindicated
- Dronedarone + Hydroxychloroquine Contraindicated
- Hydroxychloroquine + Pimozide Contraindicated
- Hydroxychloroquine + Thioridazine Contraindicated
- Hydroxychloroquine + Vandetanib Contraindicated
Frequently asked questions
Can I take Human papillomavirus vaccine with Hydroxychloroquine?
MediHelp rates the interaction as minor. Human papillomavirus vaccine and Hydroxychloroquine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Hydroxychloroquine is only a mild immunomodulator and has not been shown to meaningfully impair responses to non-live vaccines. The HPV vaccine can be given during therapy.
How serious is the interaction between Human papillomavirus vaccine and Hydroxychloroquine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No change needed; vaccinate according to the usual schedule.
What other medicines interact with Human papillomavirus vaccine?
MediHelp also lists interactions of Human papillomavirus vaccine with, for example, Antithymocyte globulin equine, Antithymocyte globulin rabbit, Atidarsagene autotemcel. The full list is on the Human papillomavirus vaccine page.
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