Drug interactions
Indacaterol + Toremifene
Severity: Moderate
Indacaterol and Toremifene: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Toremifene prolongs the QT interval in a dose-related way, and indacaterol may add to repolarization risk through adrenergic effects and low potassium. Ventricular arrhythmia risk may rise.
What this interaction means in plain words
Indacaterol and Toremifene can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Indacaterol belongs to Respiratory; Toremifene belongs to Endocrine.
Why it happens
Additive QT prolongation and beta-agonist induced hypokalemia.
What to do
Correct hypokalemia and hypomagnesemia and monitor ECG during co-use. Consider alternatives in patients with congenital long QT.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Indacaterol and Toremifene, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 7 days on the web. No card needed.
Other interactions of Indacaterol
Other interactions of Toremifene
- Amiodarone + Toremifene Contraindicated
- Dronedarone + Toremifene Contraindicated
- Nilotinib + Toremifene Contraindicated
- Pimozide + Toremifene Contraindicated
- Quinidine + Toremifene Contraindicated
- Ribociclib + Toremifene Contraindicated
Frequently asked questions
Can I take Indacaterol with Toremifene?
MediHelp rates the interaction as moderate. Indacaterol and Toremifene can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Toremifene prolongs the QT interval in a dose-related way, and indacaterol may add to repolarization risk through adrenergic effects and low potassium. Ventricular arrhythmia risk may rise.
How serious is the interaction between Indacaterol and Toremifene?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Correct hypokalemia and hypomagnesemia and monitor ECG during co-use. Consider alternatives in patients with congenital long QT.
What other medicines interact with Indacaterol?
MediHelp also lists interactions of Indacaterol with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Indacaterol page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
