Drug interactions
Indacaterol-glycopyrronium + Solriamfetol
Severity: Moderate
Indacaterol-glycopyrronium and Solriamfetol: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Solriamfetol increases blood pressure and heart rate through dopaminergic and noradrenergic reuptake inhibition. Indacaterol also has cardiovascular stimulating effects, so the combination may produce additive tachycardia and hypertension.
What this interaction means in plain words
Indacaterol-glycopyrronium and Solriamfetol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Indacaterol-glycopyrronium belongs to Respiratory; Solriamfetol belongs to Central Nervous System.
Why it happens
Additive sympathomimetic cardiovascular effects.
What to do
Monitor blood pressure and heart rate at initiation and during dose changes. Use caution in patients with cardiovascular disease and adjust therapy if hypertension or tachycardia occurs.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Indacaterol-glycopyrronium
Other interactions of Solriamfetol
- Isocarboxazid + Solriamfetol Contraindicated
- Linezolid + Solriamfetol Contraindicated
- Phenelzine + Solriamfetol Contraindicated
- Procarbazine + Solriamfetol Contraindicated
- Rasagiline + Solriamfetol Contraindicated
- Safinamide + Solriamfetol Contraindicated
Frequently asked questions
Can I take Indacaterol-glycopyrronium with Solriamfetol?
MediHelp rates the interaction as moderate. Indacaterol-glycopyrronium and Solriamfetol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Solriamfetol increases blood pressure and heart rate through dopaminergic and noradrenergic reuptake inhibition. Indacaterol also has cardiovascular stimulating effects, so the combination may produce additive tachycardia and hypertension.
How serious is the interaction between Indacaterol-glycopyrronium and Solriamfetol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate at initiation and during dose changes. Use caution in patients with cardiovascular disease and adjust therapy if hypertension or tachycardia occurs.
What other medicines interact with Indacaterol-glycopyrronium?
MediHelp also lists interactions of Indacaterol-glycopyrronium with, for example, Amisulpride, Arformoterol, Arsenic trioxide. The full list is on the Indacaterol-glycopyrronium page.
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