Drug interactions
Lasmiditan + Mitomycin
Severity: Minor
Lasmiditan and Mitomycin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lasmiditan inhibits intestinal P-glycoprotein in vitro, which could increase exposure to P-gp substrates. Clinical relevance for intravenous mitomycin is uncertain and likely small.
What this interaction means in plain words
Lasmiditan and Mitomycin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Lasmiditan belongs to Central Nervous System; Mitomycin belongs to Oncology.
Why it happens
Possible P-glycoprotein inhibition by lasmiditan; effect on parenteral mitomycin is theoretical.
What to do
No specific action is usually required; monitor for increased mitomycin toxicity during chemotherapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Mitomycin
- Bacitracin + Mitomycin Major
- Deferiprone + Mitomycin Major
- Dengue vaccine + Mitomycin Major
- Etrasimod + Mitomycin Major
- Fingolimod + Mitomycin Major
- Mitomycin + Palifermin Major
Other interactions of Lasmiditan
- Alprazolam + Lasmiditan Moderate
- Amiodarone + Lasmiditan Moderate
- Amisulpride + Lasmiditan Moderate
- Amobarbital + Lasmiditan Moderate
- Aripiprazole + Lasmiditan Moderate
- Asenapine + Lasmiditan Moderate
Frequently asked questions
Can I take Lasmiditan with Mitomycin?
MediHelp rates the interaction as minor. Lasmiditan and Mitomycin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Lasmiditan inhibits intestinal P-glycoprotein in vitro, which could increase exposure to P-gp substrates. Clinical relevance for intravenous mitomycin is uncertain and likely small.
How serious is the interaction between Lasmiditan and Mitomycin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is usually required; monitor for increased mitomycin toxicity during chemotherapy.
What other medicines interact with Mitomycin?
MediHelp also lists interactions of Mitomycin with, for example, Bacitracin, Deferiprone, Dengue vaccine. The full list is on the Mitomycin page.
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