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Drug interactions

Maraviroc + Mirtazapine

Severity: Minor

Maraviroc and Mirtazapine: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Maraviroc can cause postural hypotension, and mirtazapine can also cause orthostatic effects through alpha-1 and antihistaminic actions. Using both may increase dizziness or fainting in susceptible patients. The effect is generally modest.

What this interaction means in plain words

Maraviroc and Mirtazapine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Maraviroc belongs to Anti Virals; Mirtazapine belongs to Central Nervous System.

Evidence level: Low

Why it happens

Additive pharmacodynamic effects on blood pressure regulation.

What to do

Counsel patients to rise slowly and monitor for dizziness or hypotension, especially in older patients or those on other antihypertensives.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Frequently asked questions

Can I take Maraviroc with Mirtazapine?

MediHelp rates the interaction as minor. Maraviroc and Mirtazapine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Maraviroc can cause postural hypotension, and mirtazapine can also cause orthostatic effects through alpha-1 and antihistaminic actions. Using both may increase dizziness or fainting in susceptible patients. The effect is generally modest.

How serious is the interaction between Maraviroc and Mirtazapine?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel patients to rise slowly and monitor for dizziness or hypotension, especially in older patients or those on other antihypertensives.

What other medicines interact with Mirtazapine?

MediHelp also lists interactions of Mirtazapine with, for example, Isocarboxazid, Phenelzine, Pimozide. The full list is on the Mirtazapine page.

Full monographs, dosing and an interaction checker in the MediHelp app

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