Drug interactions
Mirtazapine + Teriflunomide
Severity: Minor
Mirtazapine and Teriflunomide: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Teriflunomide is a weak inducer of CYP1A2 and may modestly reduce mirtazapine exposure. The clinical effect is likely small but could reduce antidepressant response in some patients.
What this interaction means in plain words
Mirtazapine and Teriflunomide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Mirtazapine belongs to Central Nervous System; Teriflunomide belongs to Central Nervous System.
Why it happens
Weak CYP1A2 induction by teriflunomide increases mirtazapine metabolism.
What to do
No routine dose change is needed; monitor depressive symptoms and adjust the mirtazapine dose if response diminishes.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Mirtazapine
- Isocarboxazid + Mirtazapine Contraindicated
- Mirtazapine + Phenelzine Contraindicated
- Mirtazapine + Pimozide Contraindicated
- Mirtazapine + Procarbazine Contraindicated
- Mirtazapine + Rasagiline Contraindicated
- Mirtazapine + Selegiline Contraindicated
Other interactions of Teriflunomide
Frequently asked questions
Can I take Mirtazapine with Teriflunomide?
MediHelp rates the interaction as minor. Mirtazapine and Teriflunomide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Teriflunomide is a weak inducer of CYP1A2 and may modestly reduce mirtazapine exposure. The clinical effect is likely small but could reduce antidepressant response in some patients.
How serious is the interaction between Mirtazapine and Teriflunomide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine dose change is needed; monitor depressive symptoms and adjust the mirtazapine dose if response diminishes.
What other medicines interact with Mirtazapine?
MediHelp also lists interactions of Mirtazapine with, for example, Isocarboxazid, Phenelzine, Pimozide. The full list is on the Mirtazapine page.
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