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Drug interactions

Ropivacaine + Teriflunomide

Severity: Minor

Ropivacaine and Teriflunomide: minor interaction.

Last updated

For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.

Summary

Ropivacaine is metabolized by CYP1A2, which teriflunomide weakly induces. Any reduction in levels from a single local anesthetic dose would be minor and of little clinical importance.

What this interaction means in plain words

Ropivacaine and Teriflunomide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Ropivacaine belongs to Central Nervous System; Teriflunomide belongs to Central Nervous System.

Evidence level: Low

Why it happens

Weak CYP1A2 induction by teriflunomide may modestly increase ropivacaine metabolism.

What to do

No action needed beyond monitoring anesthetic effect.

What to ask your pharmacist

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

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Frequently asked questions

Can I take Ropivacaine with Teriflunomide?

MediHelp rates the interaction as minor. Ropivacaine and Teriflunomide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ropivacaine is metabolized by CYP1A2, which teriflunomide weakly induces. Any reduction in levels from a single local anesthetic dose would be minor and of little clinical importance.

How serious is the interaction between Ropivacaine and Teriflunomide?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No action needed beyond monitoring anesthetic effect.

What other medicines interact with Teriflunomide?

MediHelp also lists interactions of Teriflunomide with, for example, Ifosfamide, Lomustine, Amiodarone. The full list is on the Teriflunomide page.

Full monographs, dosing and an interaction checker in the MediHelp app

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