Drug interactions
Trimipramine + Vildagliptin
Severity: Minor
Trimipramine and Vildagliptin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tricyclic antidepressants may slightly alter glycemic control, so an added glucose-lowering effect with vildagliptin is possible. Clinical significance is small.
What this interaction means in plain words
Trimipramine and Vildagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Trimipramine belongs to Central Nervous System; Vildagliptin belongs to Endocrine.
Why it happens
Possible additive pharmacodynamic effect on glucose regulation; mechanism not firmly established.
What to do
Monitor blood glucose after starting or stopping trimipramine and adjust the antidiabetic regimen if control changes.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Trimipramine and Vildagliptin, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Trimipramine
- Disopyramide + Trimipramine Contraindicated
- Dofetilide + Trimipramine Contraindicated
- Ibutilide + Trimipramine Contraindicated
- Isocarboxazid + Trimipramine Contraindicated
- Pentamidine + Trimipramine Contraindicated
- Phenelzine + Trimipramine Contraindicated
Other interactions of Vildagliptin
- Ciprofloxacin + Vildagliptin Moderate
- Deflazacort + Vildagliptin Moderate
- Dexamethasone + Vildagliptin Moderate
- Gemifloxacin + Vildagliptin Moderate
- Glimepiride + Vildagliptin Moderate
- Hydrochlorothiazide-lisinopril + Vildagliptin Moderate
Frequently asked questions
Can I take Trimipramine with Vildagliptin?
MediHelp rates the interaction as minor. Trimipramine and Vildagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Tricyclic antidepressants may slightly alter glycemic control, so an added glucose-lowering effect with vildagliptin is possible. Clinical significance is small.
How serious is the interaction between Trimipramine and Vildagliptin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose after starting or stopping trimipramine and adjust the antidiabetic regimen if control changes.
What other medicines interact with Trimipramine?
MediHelp also lists interactions of Trimipramine with, for example, Disopyramide, Dofetilide, Ibutilide. The full list is on the Trimipramine page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
