藥物交互作用
Colesevelam + Liothyronine
嚴重程度: 中度
Colesevelam and Liothyronine: moderate interaction.
最後更新
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摘要
Colesevelam can bind oral thyroid hormones in the gut and reduce their absorption. This may lead to raised TSH and hypothyroid symptoms in patients on replacement.
用白話說明這項交互作用的意義
Colesevelam and Liothyronine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Colesevelam belongs to Endocrine; Liothyronine belongs to Endocrine.
為什麼會發生
Resin binding of thyroid hormone in the gastrointestinal tract decreases absorption.
處置方式
Give liothyronine at least 4 hours before colesevelam and monitor TSH after starting or changing colesevelam.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Colesevelam 的其他交互作用
Liothyronine 的其他交互作用
常見問題
Can I take Colesevelam with Liothyronine?
MediHelp rates the interaction as moderate. Colesevelam and Liothyronine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Colesevelam can bind oral thyroid hormones in the gut and reduce their absorption. This may lead to raised TSH and hypothyroid symptoms in patients on replacement.
How serious is the interaction between Colesevelam and Liothyronine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give liothyronine at least 4 hours before colesevelam and monitor TSH after starting or changing colesevelam.
What other medicines interact with Colesevelam?
MediHelp also lists interactions of Colesevelam with, for example, Amlodipine-olmesartan-hydrochlorothiazide, Amlodipine-olmesartan, Chenodiol. The full list is on the Colesevelam page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
