藥物交互作用
Amisulpride + Bromocriptine
嚴重程度: 嚴重
Amisulpride and Bromocriptine: major interaction.
最後更新
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摘要
Amisulpride is a selective D2/D3 receptor antagonist and opposes the dopaminergic action of bromocriptine. This can reduce control of Parkinson disease or hyperprolactinemia, and the agonist may in turn worsen psychosis.
用白話說明這項交互作用的意義
Amisulpride and Bromocriptine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Amisulpride belongs to Central Nervous System; Bromocriptine belongs to Central Nervous System.
為什麼會發生
Pharmacodynamic antagonism at dopamine D2/D3 receptors.
處置方式
Avoid the combination. In Parkinson disease with psychosis, use quetiapine or clozapine, and monitor symptoms and prolactin if both must be used.
可向藥師詢問的問題
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Bromocriptine 的其他交互作用
Amisulpride 的其他交互作用
常見問題
Can I take Amisulpride with Bromocriptine?
MediHelp rates the interaction as major. Amisulpride and Bromocriptine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Amisulpride is a selective D2/D3 receptor antagonist and opposes the dopaminergic action of bromocriptine. This can reduce control of Parkinson disease or hyperprolactinemia, and the agonist may in turn worsen psychosis.
How serious is the interaction between Amisulpride and Bromocriptine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination. In Parkinson disease with psychosis, use quetiapine or clozapine, and monitor symptoms and prolactin if both must be used.
What other medicines interact with Bromocriptine?
MediHelp also lists interactions of Bromocriptine with, for example, Atazanavir, Cobicistat, Darunavir. The full list is on the Bromocriptine page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
