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藥物交互作用

Amlodipine-hydrochlorothiazide-valsartan + Balsalazide

嚴重程度: 輕微

Amlodipine-hydrochlorothiazide-valsartan and Balsalazide: minor interaction.

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僅供醫療專業人員參考。本頁為簡要摘要,並非醫療建議,亦不能取代官方仿單或臨床判斷。開立處方或調劑前請務必核實。

本頁的臨床內容僅提供英文版。

摘要

The interaction is theoretical. Balsalazide is a prodrug cleaved in the colon to mesalamine, and there is no established clinically relevant renal handling interaction with hydrochlorothiazide.

用白話說明這項交互作用的意義

Amlodipine-hydrochlorothiazide-valsartan and Balsalazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Amlodipine-hydrochlorothiazide-valsartan belongs to Cardiovascular; Balsalazide belongs to Gastrointestinal Tract.

證據等級: Low

為什麼會發生

Theoretical competition for renal tubular anion secretion; not well established.

處置方式

No specific action is needed; monitor renal function periodically, as mesalamine products can affect the kidney and ARB plus diuretic therapy adds renal risk.

可向藥師詢問的問題

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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常見問題

Can I take Amlodipine-hydrochlorothiazide-valsartan with Balsalazide?

MediHelp rates the interaction as minor. Amlodipine-hydrochlorothiazide-valsartan and Balsalazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. The interaction is theoretical. Balsalazide is a prodrug cleaved in the colon to mesalamine, and there is no established clinically relevant renal handling interaction with hydrochlorothiazide.

How serious is the interaction between Amlodipine-hydrochlorothiazide-valsartan and Balsalazide?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed; monitor renal function periodically, as mesalamine products can affect the kidney and ARB plus diuretic therapy adds renal risk.

What other medicines interact with Amlodipine-hydrochlorothiazide-valsartan?

MediHelp also lists interactions of Amlodipine-hydrochlorothiazide-valsartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-hydrochlorothiazide-valsartan page.

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