藥物交互作用
Amlodipine-hydrochlorothiazide-valsartan + Balsalazide
嚴重程度: 輕微
Amlodipine-hydrochlorothiazide-valsartan and Balsalazide: minor interaction.
最後更新
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摘要
The interaction is theoretical. Balsalazide is a prodrug cleaved in the colon to mesalamine, and there is no established clinically relevant renal handling interaction with hydrochlorothiazide.
用白話說明這項交互作用的意義
Amlodipine-hydrochlorothiazide-valsartan and Balsalazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine-hydrochlorothiazide-valsartan belongs to Cardiovascular; Balsalazide belongs to Gastrointestinal Tract.
為什麼會發生
Theoretical competition for renal tubular anion secretion; not well established.
處置方式
No specific action is needed; monitor renal function periodically, as mesalamine products can affect the kidney and ARB plus diuretic therapy adds renal risk.
可向藥師詢問的問題
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Amlodipine-hydrochlorothiazide-valsartan 的其他交互作用
- Aliskiren + Amlodipine-hydrochlorothiazide-valsartan 禁忌併用
- Amlodipine-hydrochlorothiazide-valsartan + Dofetilide 禁忌併用
- Amlodipine-hydrochlorothiazide-valsartan + Sparsentan 禁忌併用
- Aceclofenac + Amlodipine-hydrochlorothiazide-valsartan 嚴重
- Aldesleukin + Amlodipine-hydrochlorothiazide-valsartan 嚴重
- Amifostine + Amlodipine-hydrochlorothiazide-valsartan 嚴重
Balsalazide 的其他交互作用
常見問題
Can I take Amlodipine-hydrochlorothiazide-valsartan with Balsalazide?
MediHelp rates the interaction as minor. Amlodipine-hydrochlorothiazide-valsartan and Balsalazide have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. The interaction is theoretical. Balsalazide is a prodrug cleaved in the colon to mesalamine, and there is no established clinically relevant renal handling interaction with hydrochlorothiazide.
How serious is the interaction between Amlodipine-hydrochlorothiazide-valsartan and Balsalazide?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No specific action is needed; monitor renal function periodically, as mesalamine products can affect the kidney and ARB plus diuretic therapy adds renal risk.
What other medicines interact with Amlodipine-hydrochlorothiazide-valsartan?
MediHelp also lists interactions of Amlodipine-hydrochlorothiazide-valsartan with, for example, Aliskiren, Dofetilide, Sparsentan. The full list is on the Amlodipine-hydrochlorothiazide-valsartan page.
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