藥物交互作用
Calcium carbonate + Vadadustat
嚴重程度: 中度
Calcium carbonate and Vadadustat: moderate interaction.
最後更新
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摘要
Calcium-based phosphate binders can bind vadadustat in the gut and lower its absorption. Reduced exposure may blunt its effect on hemoglobin.
用白話說明這項交互作用的意義
Calcium carbonate and Vadadustat can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Calcium carbonate belongs to Gastrointestinal Tract; Vadadustat belongs to Endocrine.
為什麼會發生
Binding of vadadustat by calcium-based phosphate binders in the gastrointestinal tract reduces absorption.
處置方式
Take vadadustat at least 1 hour before or 2 hours after calcium carbonate used as a phosphate binder. Monitor hemoglobin.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Calcium carbonate 的其他交互作用
Vadadustat 的其他交互作用
常見問題
Can I take Calcium carbonate with Vadadustat?
MediHelp rates the interaction as moderate. Calcium carbonate and Vadadustat can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Calcium-based phosphate binders can bind vadadustat in the gut and lower its absorption. Reduced exposure may blunt its effect on hemoglobin.
How serious is the interaction between Calcium carbonate and Vadadustat?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take vadadustat at least 1 hour before or 2 hours after calcium carbonate used as a phosphate binder. Monitor hemoglobin.
What other medicines interact with Calcium carbonate?
MediHelp also lists interactions of Calcium carbonate with, for example, Acalabrutinib, Alendronate, Amlodipine-hydrochlorothiazide-valsartan. The full list is on the Calcium carbonate page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用,並使用劑量工具。