藥物交互作用
Chlorthalidone + Magnesium
嚴重程度: 中度
Chlorthalidone and Magnesium: moderate interaction.
最後更新
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摘要
Thiazide-like diuretics promote urinary magnesium loss and can cause hypomagnesemia with chronic use. This may contribute to hypokalemia and arrhythmias.
用白話說明這項交互作用的意義
Chlorthalidone and Magnesium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Chlorthalidone belongs to Cardiovascular; Magnesium belongs to Gastrointestinal Tract.
為什麼會發生
Distal tubule effects, including reduced expression of magnesium transport channels, increase renal magnesium excretion.
處置方式
Check serum magnesium and potassium periodically. Replace magnesium if low.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Magnesium 的其他交互作用
Chlorthalidone 的其他交互作用
常見問題
Can I take Chlorthalidone with Magnesium?
MediHelp rates the interaction as moderate. Chlorthalidone and Magnesium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Thiazide-like diuretics promote urinary magnesium loss and can cause hypomagnesemia with chronic use. This may contribute to hypokalemia and arrhythmias.
How serious is the interaction between Chlorthalidone and Magnesium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check serum magnesium and potassium periodically. Replace magnesium if low.
What other medicines interact with Magnesium?
MediHelp also lists interactions of Magnesium with, for example, Ciprofloxacin, Pancuronium, Rocuronium. The full list is on the Magnesium page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
