藥物交互作用
Lemborexant + Micafungin
嚴重程度: 輕微
Lemborexant and Micafungin: minor interaction.
最後更新
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本頁的臨床內容僅提供英文版。
摘要
Weak CYP3A4 inhibitors raise lemborexant exposure, increasing the risk of next-day somnolence and impaired alertness. Micafungin's CYP3A4 inhibition is weak, so the effect is likely small.
用白話說明這項交互作用的意義
Lemborexant and Micafungin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Lemborexant belongs to Central Nervous System; Micafungin belongs to Anti Fungals.
為什麼會發生
Weak CYP3A4 inhibition by micafungin reduces lemborexant clearance.
處置方式
Follow labeling for weak CYP3A4 inhibitors by limiting lemborexant to the lower recommended nightly dose, and counsel on next-day drowsiness.
可向藥師詢問的問題
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Micafungin 的其他交互作用
Lemborexant 的其他交互作用
常見問題
Can I take Lemborexant with Micafungin?
MediHelp rates the interaction as minor. Lemborexant and Micafungin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Weak CYP3A4 inhibitors raise lemborexant exposure, increasing the risk of next-day somnolence and impaired alertness. Micafungin's CYP3A4 inhibition is weak, so the effect is likely small.
How serious is the interaction between Lemborexant and Micafungin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Follow labeling for weak CYP3A4 inhibitors by limiting lemborexant to the lower recommended nightly dose, and counsel on next-day drowsiness.
What other medicines interact with Micafungin?
MediHelp also lists interactions of Micafungin with, for example, Lomitapide, Saccharomyces boulardii, Sirolimus. The full list is on the Micafungin page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
