Drug interactions
Amlodipine-perindopril + Lanthanum carbonate
Severity: Minor
Amlodipine-perindopril and Lanthanum carbonate: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Lanthanum can bind to other oral drugs in the gut, which may reduce perindopril absorption. The antihypertensive effect could be weakened.
What this interaction means in plain words
Amlodipine-perindopril and Lanthanum carbonate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Amlodipine-perindopril belongs to Cardiovascular; Lanthanum carbonate belongs to Miscellaneous.
Why it happens
Binding of perindopril by lanthanum cations in the gastrointestinal tract reduces absorption.
What to do
Give perindopril at least 2 hours before or after lanthanum carbonate. Monitor blood pressure.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Amlodipine-perindopril
- Aliskiren + Amlodipine-perindopril Contraindicated
- Amlodipine-perindopril + Protein a column Contraindicated
- Amlodipine-perindopril + Sacubitril / valsartan Contraindicated
- Amifostine + Amlodipine-perindopril Major
- Amiloride + Amlodipine-perindopril Major
- Amlodipine-perindopril + Azilsartan Major
Other interactions of Lanthanum carbonate
Frequently asked questions
Can I take Amlodipine-perindopril with Lanthanum carbonate?
MediHelp rates the interaction as minor. Amlodipine-perindopril and Lanthanum carbonate have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Lanthanum can bind to other oral drugs in the gut, which may reduce perindopril absorption. The antihypertensive effect could be weakened.
How serious is the interaction between Amlodipine-perindopril and Lanthanum carbonate?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give perindopril at least 2 hours before or after lanthanum carbonate. Monitor blood pressure.
What other medicines interact with Amlodipine-perindopril?
MediHelp also lists interactions of Amlodipine-perindopril with, for example, Aliskiren, Protein a column, Sacubitril / valsartan. The full list is on the Amlodipine-perindopril page.
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