Drug interactions
Ciclesonide + Rucaparib
Severity: Minor
Ciclesonide and Rucaparib: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Rucaparib weakly inhibits CYP3A4 and may slightly increase ciclesonide exposure. Clinical consequences are unlikely with inhaled dosing.
What this interaction means in plain words
Ciclesonide and Rucaparib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ciclesonide belongs to Respiratory; Rucaparib belongs to Oncology.
Why it happens
Weak CYP3A4 inhibition by rucaparib reduces metabolism of ciclesonide.
What to do
No routine dose change is needed; watch for signs of systemic corticosteroid excess with prolonged use.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ciclesonide
- Ciclesonide + Ritonavir Major
- Apalutamide + Ciclesonide Moderate
- Atazanavir + Ciclesonide Moderate
- Ceritinib + Ciclesonide Moderate
- Ciclesonide + Clarithromycin Moderate
- Ciclesonide + Cobicistat Moderate
Other interactions of Rucaparib
- Cisapride + Rucaparib Major
- Ergotamine + Rucaparib Major
- Pimozide + Rucaparib Major
- Alfuzosin + Rucaparib Moderate
- Aripiprazole + Rucaparib Moderate
- Atorvastatin + Rucaparib Moderate
Frequently asked questions
Can I take Ciclesonide with Rucaparib?
MediHelp rates the interaction as minor. Ciclesonide and Rucaparib have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Rucaparib weakly inhibits CYP3A4 and may slightly increase ciclesonide exposure. Clinical consequences are unlikely with inhaled dosing.
How serious is the interaction between Ciclesonide and Rucaparib?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine dose change is needed; watch for signs of systemic corticosteroid excess with prolonged use.
What other medicines interact with Ciclesonide?
MediHelp also lists interactions of Ciclesonide with, for example, Ritonavir, Apalutamide, Atazanavir. The full list is on the Ciclesonide page.
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