Drug interactions
Elagolix + Fenofibric acid
Severity: Minor
Elagolix and Fenofibric acid: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Elagolix is a weak to moderate CYP3A4 inducer, but fenofibric acid depends little on CYP3A4 for elimination. Any reduction in exposure is expected to be small and of limited clinical relevance.
What this interaction means in plain words
Elagolix and Fenofibric acid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Elagolix belongs to Musculoskeletal; Fenofibric acid belongs to Cardiovascular.
Why it happens
Weak to moderate CYP3A induction by elagolix, which is a minor pathway for fenofibric acid.
What to do
No empiric dose change is required; monitor lipids as usual.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fenofibric acid
- Atorvastatin + Fenofibric acid Moderate
- Chlorpropamide + Fenofibric acid Moderate
- Cholestyramine + Fenofibric acid Moderate
- Cholic acid + Fenofibric acid Moderate
- Colchicine + Fenofibric acid Moderate
- Colestipol + Fenofibric acid Moderate
Other interactions of Elagolix
- Cyclosporin + Elagolix Contraindicated
- Elagolix + Gemfibrozil Contraindicated
- Desogestrel-ethinyl estradiol + Elagolix Major
- Elagolix + Erythromycin Major
- Elagolix + Ethinyl estradiol-drospirenone Major
- Elagolix + Ethinyl estradiol-levonorgestrel Major
Frequently asked questions
Can I take Elagolix with Fenofibric acid?
MediHelp rates the interaction as minor. Elagolix and Fenofibric acid have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Elagolix is a weak to moderate CYP3A4 inducer, but fenofibric acid depends little on CYP3A4 for elimination. Any reduction in exposure is expected to be small and of limited clinical relevance.
How serious is the interaction between Elagolix and Fenofibric acid?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No empiric dose change is required; monitor lipids as usual.
What other medicines interact with Fenofibric acid?
MediHelp also lists interactions of Fenofibric acid with, for example, Atorvastatin, Chlorpropamide, Cholestyramine. The full list is on the Fenofibric acid page.
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