Drug interactions
Elagolix + Ticlopidine
Severity: Minor
Elagolix and Ticlopidine: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Elagolix is a weak-to-moderate CYP3A4 inducer, so it could lower exposure to CYP3A4 substrates. Ticlopidine is not a sensitive CYP3A4 substrate, and the clinical impact is likely small.
What this interaction means in plain words
Elagolix and Ticlopidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Elagolix belongs to Musculoskeletal; Ticlopidine belongs to Cardiovascular.
Why it happens
Possible CYP3A4 induction by elagolix reducing ticlopidine concentrations.
What to do
No routine adjustment is required; monitor clinical response and platelet function if concerns arise.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ticlopidine
Other interactions of Elagolix
- Cyclosporin + Elagolix Contraindicated
- Elagolix + Gemfibrozil Contraindicated
- Desogestrel-ethinyl estradiol + Elagolix Major
- Elagolix + Erythromycin Major
- Elagolix + Ethinyl estradiol-drospirenone Major
- Elagolix + Ethinyl estradiol-levonorgestrel Major
Frequently asked questions
Can I take Elagolix with Ticlopidine?
MediHelp rates the interaction as minor. Elagolix and Ticlopidine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Elagolix is a weak-to-moderate CYP3A4 inducer, so it could lower exposure to CYP3A4 substrates. Ticlopidine is not a sensitive CYP3A4 substrate, and the clinical impact is likely small.
How serious is the interaction between Elagolix and Ticlopidine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is required; monitor clinical response and platelet function if concerns arise.
What other medicines interact with Ticlopidine?
MediHelp also lists interactions of Ticlopidine with, for example, Mavacamten, Abrocitinib, Acetylsalicylic acid. The full list is on the Ticlopidine page.
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