Drug interactions
Fenofibrate + Stiripentol
Severity: Minor
Fenofibrate and Stiripentol: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Stiripentol both inhibits and induces CYP3A4, so effects on substrates are unpredictable. Because fenofibrate depends little on CYP3A4, a meaningful change in its exposure is unlikely.
What this interaction means in plain words
Fenofibrate and Stiripentol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Fenofibrate belongs to Cardiovascular; Stiripentol belongs to Central Nervous System.
Why it happens
Stiripentol has mixed CYP3A4 inhibitory and inducing effects, which have limited relevance to fenofibric acid clearance.
What to do
No empiric dose change is needed. Check the lipid profile and watch for adverse effects if the clinical picture changes.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Fenofibrate
- Atorvastatin + Fenofibrate Moderate
- Cholestyramine + Fenofibrate Moderate
- Cholic acid + Fenofibrate Moderate
- Colchicine + Fenofibrate Moderate
- Colestipol + Fenofibrate Moderate
- Cyclosporine + Fenofibrate Moderate
Other interactions of Stiripentol
Frequently asked questions
Can I take Fenofibrate with Stiripentol?
MediHelp rates the interaction as minor. Fenofibrate and Stiripentol have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Stiripentol both inhibits and induces CYP3A4, so effects on substrates are unpredictable. Because fenofibrate depends little on CYP3A4, a meaningful change in its exposure is unlikely.
How serious is the interaction between Fenofibrate and Stiripentol?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No empiric dose change is needed. Check the lipid profile and watch for adverse effects if the clinical picture changes.
What other medicines interact with Fenofibrate?
MediHelp also lists interactions of Fenofibrate with, for example, Atorvastatin, Cholestyramine, Cholic acid. The full list is on the Fenofibrate page.
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