Drug interactions
Human papillomavirus vaccine + Secukinumab
Severity: Minor
Human papillomavirus vaccine and Secukinumab: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Secukinumab appears to have limited effect on responses to non-live vaccines, and the HPV vaccine is safe to give. A modest reduction in response cannot be fully excluded.
What this interaction means in plain words
Human papillomavirus vaccine and Secukinumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Human papillomavirus vaccine belongs to Miscellaneous; Secukinumab belongs to Miscellaneous.
Why it happens
IL-17A blockade is selective and is not expected to substantially impair humoral vaccine responses.
What to do
Complete vaccinations before starting if convenient; otherwise vaccinate on schedule without interruption of therapy.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Human papillomavirus vaccine
- Antithymocyte globulin equine + Human papillomavirus vaccine Moderate
- Antithymocyte globulin rabbit + Human papillomavirus vaccine Moderate
- Atidarsagene autotemcel + Human papillomavirus vaccine Moderate
- Belimumab + Human papillomavirus vaccine Moderate
- Cortisone + Human papillomavirus vaccine Moderate
- Cyclosporine + Human papillomavirus vaccine Moderate
Other interactions of Secukinumab
- Adenovirus types 4 and 7 live + Secukinumab Major
- Bcg vaccine live + Secukinumab Major
- Influenza virus vaccine quadrivalent intranasal + Secukinumab Major
- Measles mumps and rubella vaccine live + Secukinumab Major
- Measles mumps and rubella vaccine + Secukinumab Major
- Measles mumps rubella and varicella vaccine live + Secukinumab Major
Frequently asked questions
Can I take Human papillomavirus vaccine with Secukinumab?
MediHelp rates the interaction as minor. Human papillomavirus vaccine and Secukinumab have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Secukinumab appears to have limited effect on responses to non-live vaccines, and the HPV vaccine is safe to give. A modest reduction in response cannot be fully excluded.
How serious is the interaction between Human papillomavirus vaccine and Secukinumab?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Complete vaccinations before starting if convenient; otherwise vaccinate on schedule without interruption of therapy.
What other medicines interact with Human papillomavirus vaccine?
MediHelp also lists interactions of Human papillomavirus vaccine with, for example, Antithymocyte globulin equine, Antithymocyte globulin rabbit, Atidarsagene autotemcel. The full list is on the Human papillomavirus vaccine page.
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