藥物交互作用
Magnesium hydroxide + Sodium polystyrene sulfonate
嚴重程度: 中度
Magnesium hydroxide and Sodium polystyrene sulfonate: moderate interaction.
最後更新
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摘要
Magnesium hydroxide taken with sodium polystyrene sulfonate can lead to metabolic alkalosis because the resin binds the magnesium, leaving bicarbonate unneutralized. Rarely, intestinal obstruction from non-absorbable antacid and resin has been described.
用白話說明這項交互作用的意義
Magnesium hydroxide and Sodium polystyrene sulfonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Magnesium hydroxide belongs to Gastrointestinal Tract; Sodium polystyrene sulfonate belongs to Miscellaneous.
為什麼會發生
The resin binds magnesium in the gut, preventing neutralization of bicarbonate and leading to systemic alkalosis.
處置方式
Avoid giving magnesium-containing antacids or laxatives with the resin, and separate doses by at least 2 hours if both are needed. Monitor acid-base status and electrolytes.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Magnesium hydroxide 的其他交互作用
Sodium polystyrene sulfonate 的其他交互作用
常見問題
Can I take Magnesium hydroxide with Sodium polystyrene sulfonate?
MediHelp rates the interaction as moderate. Magnesium hydroxide and Sodium polystyrene sulfonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Magnesium hydroxide taken with sodium polystyrene sulfonate can lead to metabolic alkalosis because the resin binds the magnesium, leaving bicarbonate unneutralized. Rarely, intestinal obstruction from non-absorbable antacid and resin has been described.
How serious is the interaction between Magnesium hydroxide and Sodium polystyrene sulfonate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid giving magnesium-containing antacids or laxatives with the resin, and separate doses by at least 2 hours if both are needed. Monitor acid-base status and electrolytes.
What other medicines interact with Magnesium hydroxide?
MediHelp also lists interactions of Magnesium hydroxide with, for example, Ciprofloxacin, Dolutegravir, Gemifloxacin. The full list is on the Magnesium hydroxide page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
