Drug interactions
Chlorpromazine + Porfimer
Severity: Moderate
Chlorpromazine and Porfimer: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Porfimer is a photosensitizer used in photodynamic therapy, and chlorpromazine is itself phototoxic. Combined use may heighten skin photosensitivity and the risk of burns after light exposure.
What this interaction means in plain words
Chlorpromazine and Porfimer can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Chlorpromazine belongs to Central Nervous System; Porfimer belongs to Miscellaneous.
Why it happens
Additive photosensitizing effects.
What to do
Reinforce strict light protection during the photosensitivity period after porfimer. Consider holding chlorpromazine if feasible and clinically safe.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Chlorpromazine
- Chlorpromazine + Dofetilide Contraindicated
- Chlorpromazine + Dronedarone Contraindicated
- Chlorpromazine + Droperidol Contraindicated
- Chlorpromazine + Ibutilide Contraindicated
- Chlorpromazine + Metrizamide Contraindicated
- Chlorpromazine + Panobinostat Contraindicated
Other interactions of Porfimer
Frequently asked questions
Can I take Chlorpromazine with Porfimer?
MediHelp rates the interaction as moderate. Chlorpromazine and Porfimer can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Porfimer is a photosensitizer used in photodynamic therapy, and chlorpromazine is itself phototoxic. Combined use may heighten skin photosensitivity and the risk of burns after light exposure.
How serious is the interaction between Chlorpromazine and Porfimer?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Reinforce strict light protection during the photosensitivity period after porfimer. Consider holding chlorpromazine if feasible and clinically safe.
What other medicines interact with Chlorpromazine?
MediHelp also lists interactions of Chlorpromazine with, for example, Dofetilide, Dronedarone, Droperidol. The full list is on the Chlorpromazine page.
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