Drug interactions
Elagolix + Ertugliflozin-sitagliptin
Severity: Minor
Elagolix and Ertugliflozin-sitagliptin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Elagolix can inhibit P-glycoprotein and may modestly increase sitagliptin levels. The change is unlikely to matter clinically given sitagliptin's wide therapeutic margin.
What this interaction means in plain words
Elagolix and Ertugliflozin-sitagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Elagolix belongs to Musculoskeletal; Ertugliflozin-sitagliptin belongs to Endocrine.
Why it happens
Inhibition of P-glycoprotein efflux of sitagliptin by elagolix.
What to do
No routine adjustment is required. Monitor tolerability and glycemic control.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Ertugliflozin-sitagliptin
Other interactions of Elagolix
- Cyclosporin + Elagolix Contraindicated
- Elagolix + Gemfibrozil Contraindicated
- Desogestrel-ethinyl estradiol + Elagolix Major
- Elagolix + Erythromycin Major
- Elagolix + Ethinyl estradiol-drospirenone Major
- Elagolix + Ethinyl estradiol-levonorgestrel Major
Frequently asked questions
Can I take Elagolix with Ertugliflozin-sitagliptin?
MediHelp rates the interaction as minor. Elagolix and Ertugliflozin-sitagliptin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Elagolix can inhibit P-glycoprotein and may modestly increase sitagliptin levels. The change is unlikely to matter clinically given sitagliptin's wide therapeutic margin.
How serious is the interaction between Elagolix and Ertugliflozin-sitagliptin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: No routine adjustment is required. Monitor tolerability and glycemic control.
What other medicines interact with Ertugliflozin-sitagliptin?
MediHelp also lists interactions of Ertugliflozin-sitagliptin with, for example, Albiglutide, Aripiprazole, Asenapine. The full list is on the Ertugliflozin-sitagliptin page.
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