Drug interactions
Porfimer + Ticlopidine
Severity: Moderate
Porfimer and Ticlopidine: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Porfimer is a photosensitizer for photodynamic therapy. Agents that reduce thromboxane A2 release or platelet function may reduce the effect of the therapy, because part of its tumor-destroying effect depends on vascular occlusion.
What this interaction means in plain words
Porfimer and Ticlopidine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Porfimer belongs to Miscellaneous; Ticlopidine belongs to Cardiovascular.
Why it happens
Antiplatelet activity may reduce the vascular-mediated component of photodynamic tissue damage.
What to do
Consider whether ticlopidine can be interrupted around photodynamic therapy, balancing thrombotic risk. Monitor treatment response.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Ticlopidine
Other interactions of Porfimer
Frequently asked questions
Can I take Porfimer with Ticlopidine?
MediHelp rates the interaction as moderate. Porfimer and Ticlopidine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Porfimer is a photosensitizer for photodynamic therapy. Agents that reduce thromboxane A2 release or platelet function may reduce the effect of the therapy, because part of its tumor-destroying effect depends on vascular occlusion.
How serious is the interaction between Porfimer and Ticlopidine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Consider whether ticlopidine can be interrupted around photodynamic therapy, balancing thrombotic risk. Monitor treatment response.
What other medicines interact with Ticlopidine?
MediHelp also lists interactions of Ticlopidine with, for example, Mavacamten, Abrocitinib, Acetylsalicylic acid. The full list is on the Ticlopidine page.
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