藥物交互作用
Eltrombopag + Magnesium sulphate
嚴重程度: 中度
Eltrombopag and Magnesium sulphate: moderate interaction.
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摘要
Eltrombopag chelates polyvalent cations in the gut, and oral magnesium sulphate binds it, reducing eltrombopag absorption considerably. Platelet response can fall.
用白話說明這項交互作用的意義
Eltrombopag and Magnesium sulphate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Eltrombopag belongs to Miscellaneous; Magnesium sulphate belongs to Cardiovascular.
為什麼會發生
Chelation of eltrombopag by magnesium in the gastrointestinal tract
處置方式
Take eltrombopag at least 2 hours before or 4 hours after magnesium products, and monitor platelet counts.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Magnesium sulphate 的其他交互作用
Eltrombopag 的其他交互作用
常見問題
Can I take Eltrombopag with Magnesium sulphate?
MediHelp rates the interaction as moderate. Eltrombopag and Magnesium sulphate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Eltrombopag chelates polyvalent cations in the gut, and oral magnesium sulphate binds it, reducing eltrombopag absorption considerably. Platelet response can fall.
How serious is the interaction between Eltrombopag and Magnesium sulphate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take eltrombopag at least 2 hours before or 4 hours after magnesium products, and monitor platelet counts.
What other medicines interact with Magnesium sulphate?
MediHelp also lists interactions of Magnesium sulphate with, for example, Amikacin, Amphotericin b deoxycholate, Atracurium. The full list is on the Magnesium sulphate page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
