藥物交互作用
Magnesium + Sodium polystyrene sulfonate
嚴重程度: 中度
Magnesium and Sodium polystyrene sulfonate: moderate interaction.
最後更新
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摘要
Sodium polystyrene sulfonate binds magnesium in the gut, so it may lower magnesium and cause hypomagnesemia with prolonged use. The legacy concern of raised magnesium levels is not well supported, and the mechanism is poorly characterized.
用白話說明這項交互作用的意義
Magnesium and Sodium polystyrene sulfonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Magnesium belongs to Gastrointestinal Tract; Sodium polystyrene sulfonate belongs to Miscellaneous.
為什麼會發生
The resin exchanges sodium for cations including magnesium in the intestinal lumen, increasing fecal magnesium loss and also binding oral magnesium.
處置方式
Monitor serum magnesium, potassium and calcium during repeated resin use. Separate oral magnesium from the resin by at least 3 hours and replace magnesium if low.
可向藥師詢問的問題
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Magnesium 的其他交互作用
Sodium polystyrene sulfonate 的其他交互作用
常見問題
Can I take Magnesium with Sodium polystyrene sulfonate?
MediHelp rates the interaction as moderate. Magnesium and Sodium polystyrene sulfonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sodium polystyrene sulfonate binds magnesium in the gut, so it may lower magnesium and cause hypomagnesemia with prolonged use. The legacy concern of raised magnesium levels is not well supported, and the mechanism is poorly characterized.
How serious is the interaction between Magnesium and Sodium polystyrene sulfonate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum magnesium, potassium and calcium during repeated resin use. Separate oral magnesium from the resin by at least 3 hours and replace magnesium if low.
What other medicines interact with Magnesium?
MediHelp also lists interactions of Magnesium with, for example, Ciprofloxacin, Pancuronium, Rocuronium. The full list is on the Magnesium page.
在 MediHelp App 中取得完整藥品專論、劑量資訊與交互作用檢查
在 MediHelp App 中開啟完整參考資料、檢查多種藥物間的交互作用，並使用劑量工具。
