MediHelp
Drug interactions A–Z
Known drug-drug interactions with severity, mechanism and clinical management.
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
- clopidogrel + heparin major
- clopidogrel + omega-3 fatty acids moderate
- Clopidogrel + Omega-3-acid ethyl esters moderate
- clopidogrel + omeprazole major
- clopidogrel + pantoprazole moderate
- clopidogrel + prednisone moderate
- clopidogrel + rosuvastatin moderate
- clopidogrel + warfarin major
- clozapine + fluvoxamine major
- clozapine + ritonavir major
- clozapine + smoking (nicotine replacement) major
- clozapine + smoking cessation (bupropion/varenicline) major
- clozapine + smoking cessation (fluvoxamine) major
- clozapine + valproate major
- cobicistat + triazolam contraindicated
- colchicine + ritonavir contraindicated
- colchicine + verapamil major
- conivaptan + ketoconazole contraindicated
- cyclosporine + ramipril moderate
- dabigatran + dronedarone major
- dabigatran + ketoconazole major
- dantrolene + gabapentin moderate
- dapagliflozin + sacubitril/valsartan moderate
- daptomycin + simvastatin major
- desmopressin + ibuprofen major
- desmopressin + sertraline major
- dexamethasone + diclofenac moderate
- Dexamethasone + Hydroxyzine moderate
- Dexamethasone + Ketorolac major
- dexamethasone + metamizole (dipyrone) moderate
- Dexlansoprazole + Domperidone moderate
- dexlansoprazole + ondansetron moderate
- dextromethorphan + duloxetine major
- dextromethorphan + linezolid contraindicated
- dextromethorphan + phenelzine contraindicated
- dextromethorphan + selegiline contraindicated
- dextrose 5% + iron sucrose contraindicated
- diazepam + mirtazapine moderate
- Diclofenac + Escitalopram major
- diclofenac + gentamicin moderate
- diclofenac + ibuprofen major
- Diclofenac + Piroxicam major
- diclofenac potassium + ibuprofen major
- digoxin + doxycycline moderate
- Digoxin + Furosemide major
- Digoxin + Gentamicin major
- Digoxin + Metoprolol moderate
- Digoxin + Nebivolol moderate
- digoxin + pantoprazole moderate
- digoxin + sucralfate moderate
- Digoxin + Theophylline moderate
- Digoxin + Torsemide major
- digoxin + verapamil major
- dofetilide + hydrochlorothiazide contraindicated
- dofetilide + ketoconazole contraindicated
- dofetilide + verapamil contraindicated
- dolutegravir + rifampin major
- domperidone + erythromycin major
- domperidone + lansoprazole moderate
- domperidone + omeprazole moderate
- domperidone + pantoprazole moderate
- Domperidone + Polyethylene Glycol 3350 moderate
- domperidone + rabeprazole moderate
- doxazosin + methyldopa moderate
- doxazosin + nifedipine moderate
- doxazosin + verapamil moderate
- doxycycline + iron (oral) moderate
- doxycycline + isotretinoin major
- dronedarone + ketoconazole contraindicated
- duloxetine + linezolid contraindicated
- duloxetine + paroxetine major
- edoxaban + rifampin major
- Empagliflozin + Sulpiride moderate
- empagliflozin + torsemide moderate
- Enalapril + Hydrochlorothiazide moderate
- enalapril + lithium major
- enoxaparin + piperacillin moderate
- eplerenone + ketoconazole contraindicated
- ergotamine + ritonavir contraindicated
- Erythromycin + Theophylline major
- Escitalopram + Orphenadrine moderate
- Escitalopram + Propranolol moderate
- Escitalopram + Sulpiride major
- escitalopram + valproic acid moderate
- Esomeprazole + Levothyroxine moderate
- Esomeprazole + Sulpiride moderate
- ethanol (alcohol) + pregabalin moderate
- ethanol + metronidazole contraindicated
- ethinyl estradiol (combined ocp) + rifampin major
- ethinyl estradiol + lamotrigine major
- ethinyl estradiol/gestodene + fluconazole moderate
- Ethinylestradiol and Cyproterone Acetate + Fluconazole moderate
- etoricoxib + venlafaxine moderate
- famotidine + ketoconazole moderate
- fenofibrate + valproic acid moderate
- ferrous fumarate + magnesium glycinate moderate
- ferrous fumarate + pantoprazole moderate
- flibanserin + ketoconazole contraindicated
- fluconazole + ketoconazole major
- fluconazole + levofloxacin moderate
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